«Captopril": indications, manual



Indications for "captopril" are: hypertension, kardimiopatiya, disorders of left ventricle after myocardial infarction, diabetic nephropathy and diabetes mellitus of the first type.

«Captopril" taken one hour before meals.The dosage and duration of treatment is determined by the doctor.When hypertension drug begin to take 12.5 mg twice a day.If necessary, the daily amount is gradually increased (every 2-4 weeks) until the optimum therapeutic effect.The supporting amount is 25 mg (1 tablet) 2-3 times a day.In exacerbations of the maximum daily dose should not exceed 6 tablets (25 mg).

In renal and renovascular hypertension initial dose is 6.25 mg (three times daily), maintenance - 25 mg three times a day.For treatment of chronic cardiac insufficiency "Capto
pril" begin to receive a dose of 6.25 mg three times a day.Every 2-3 weeks it was gradually raised and adjusted to an optimum quantity of 25-50 mg (2-3 times a day).For elderly patients dose picked individually, therapy is started with a dose of 6.25 mg twice a day.If possible, it is maintained at this level.

Contraindications "captopril»



«Captopril" is contraindicated in the following cases: in case of hypersensitivity to the active substance, angioedema, expressed violations of the kidneys, liver, kidney transplant, with azotemia.The drug is not used for primary hyperaldosteronism, hyperkalaemia, bilateral renal artery stenosis, cardiogenic shock, hypotension, mitral stenosis, aortic stenosis."Captopril" can not be used before the age of 18 years, during pregnancy and lactation.

Side effects "captopril»



Adverse action "captopril" include: headache, dizziness, CNS depression, ataxia, seizures, confusion, fatigue, depression, blurred vision and smell.May occur: tingling or numbness in the extremities, bronchospasm, dyspnea, bronchitis, non-productive cough, cardiac arrhythmias, orthostatic hypotension, angina pectoris, tachycardia, and myocardial infarction.The drug can cause exfoliative dermatitis, skin rash, urticaria, toxic epidermal necrolysis, anaphylaxis, photodermatitis, alopecia, angioedema.