mechanism of drug action



Regardless of the issue, each tablet of the drug "Chondroxide" contains 250 mg of active ingredient - chondroitin sulfate, which belongs to a group of proofreaders metabolism of cartilage and bone.This substance is involved in the construction of bone and cartilage tissue, prevents them from degenerative changes, promotes the production of the joint (synovial) fluid, normalizes metabolism processes in the joint tissues and promote their regeneration.Additionally, chondroitin has analgesic activity and reduces the severity of inflammation in the joints, thereby increasing their mobility.Also, the drug reduces the need for administration of nonsteroidal anti-inflammatory drugs. These drugs, in this c
ase are Ortophenum, diclofenac, indomethacin, etc.



Although chondroitin that accumulates mainly in the tissues of the joints, its bioavailability is only 13% (the remainder is excreted by the kidneys), and the maximum concentration is attained only after 48 hours after administration.Therefore, to achieve the therapeutic effect of the drug is usually given long courses - from 6 months.After discontinuation of the drug effect is also preserved for a long time, and often the need for re-application is not available.However, individual readings can be repeated courses of the drug.

Indications, contraindications, how to use



The most common pill "Chondroxide" prescribed for diseases associated with degenerative and dystrophic changes in joints and the spine, such as low back pain, arthritis, osteoporosis, and the like, but in some casesused for fractures and after surgical intervention in bone or cartilage tissue to accelerate its healing. should not diagnose yourself - in any case, consult your physician.

According to the instructions, the use of "Chondroxide" is contraindicated in pregnancy, breast-feeding, as well as any kind of bleeding, becausethe drug reduces blood clotting.

initial rate is usually 500 mg (2 tablets) twice a day, to be washed down with a little water.The average duration of a course of 6 months.However, the dosage, and duration of the reception circuit is always determined by the physician individually depending on the type of disease, location of the lesion and its severity.

Side effects from the drug are relatively rare, but an overdose can occur allergic, and in severe cases, hemorrhagic reactions or nausea, vomiting, etc.