Instructions for Use "Locri»

«Lokren" is prescribed for hypertension and to prevent strokes.Pills "Locri" Inside, not chewing and drinking water.The initial dose is 10 mg per day.If during one or two weeks of treatment is ineffective, the amount of the drug is increased to 20 mg per day.Usually not used dose "Lokren" exceeding 20 mg, due to the fact that in this case there is no statistically significant increase in the effect.The maximum daily dose "Locri" - 40 mg. In patients with severe renal failure, the daily amount of the drug is reduced to 5 mg, with mild hepatic and renal failure do not need to adjust the dose.

If overdose may develop syncope, dizziness, shortness of breath, arrhythmia, bradycardia, heart failure, seizures, bronchospasm, a sudden drop in blood pressure.To eliminate these symptoms intravenous "Isoprenaline" in t
he amount of 25 micrograms, carry out gastric lavage, appoint absorbent agent.

contraindications, special conditions of use "Locri»

Medicament "Lokren" is contraindicated in cardiogenic shock, Prinzmetal angina, AV-block II and III degree (violation of the electrical impulse from the atria to the ventricles), chronic heart failure IIB-stage III, severe bradycardia (reduced heart rate), and hypersensitivity kardiomigalii, lowering blood pressure."Lokren" is not used in children and adolescents up to the age of eighteen years due to a lack of clinical trials.

wary appoint "Lokren" with AV-blockade of I degree, hepatic and renal failure, depression, thyroid disease, with peripheral vascular disease, and chronic obstructive pulmonary disease, diabetes, myasthenia gravis (fatigue of muscles) in patients with chroniccirculatory failure. not recommended "Lokren" during pregnancy and breastfeeding period, with the exception of strict indications.

Side effects "Locri»

«Lokren" can cause negative side effects: fatigue, weakness, drowsiness or insomnia, dizziness, headache, nightmares, depression, anxiety, muscle weakness, hallucinations, short-term memory loss, confusion - the central nervous system.

may develop weakening of myocardial contractility, sinus bradycardia, arrhythmia, palpitations, AV-blockade, chest pain, sudden drop in blood pressure, swelling of the ankles, feet or lower legs - the part of the cardiovascular system.On the part of the digestive system drug can cause nausea and vomiting, abdominal pain, change in taste, constipation or diarrhea, abnormal liver function.Other side effects are described in the annotations to the drug.