"Nitrosobid" is a group of vasodilating agents, nitrate.The trade name of the drug - "Nitrosorbid."Generic name - isosorbide dinitrate.Available in white pills ploskotsilindricheskoy form.One tablet "Nitrosorbid" contains 10 mg of active substance - izorbida dinitrate and Excipients: 80 mg of sucrase, 9.5 mg of potato starch, 0.5 mg of calcium stearate.
"Nitrosorbid" has a relaxing effect on vascular smooth muscle.It has a vasodilating effect.It has an effect on peripheral arteries and veins, which in turn svogo reduces the venous return to the heart and thus reduces the filling pressure of the left ventricle.It promotes the expansion of blood vessels and thus significantly reduces blood pressure.Relieves koronarospaszm.Improves gipodinamiku in patients with chronic heart failure
quickly absorbed through the oral mucosa.Bioavailability when receiving sublingual - 60 percent, when taken orally - no more than 22 percent.When administered for one hour maximum concentration of the drug.The half-life of the drug substance ranges from 2.5 to 5 hours.Because the body excreted by the kidneys as metabolites. During pregnancy, the use of "Nitrosorbid" is possible only after the ratio of benefits to the mother and the risk to the fetus.
"Nitrororbid" prescribed as anti-anginal agent for the prevention and relief of angina attacks, including - after myocardial infarction in the complex therapy in chronic heart failure, including atsevere disease during chest pain.
is not recommended to use the drug in case of hypersensitivity to one or more components of the medication, poor circulation, acute cardiogenic shock, acute myocardial infarction, cardiac tamponade, stroke, arterial hypotension (systolic blood pressure less than 90 mm Hg. v.), cerebral hemorrhage, closed form of glaucoma with high intraocular pressure, and while receiving inhibitors of fructose intolerance. Effect of the drug, its efficacy and safety of the state of the persons under 18 years of age have not been established.
Dosing and Administration
"Nitrosorbid" are inside or under the tongue.
to relieve angina attacks 1 tablet (10 mg) taken sublingually.To speed up the effect of the tablet should be chewed.
To prevent angina appoint 10 mg of nitroglycerin (1 tablet) 4-5 times.If insufficient action in the first five days, the dosage can be increased to 60-120 mg per day.
When combined therapy "Nitrosorbid" appoint 10-20 mg 3-4 times a day.Apply "Nitrosorbid" can only be in accordance with the doctor's recommendations and in accordance with the recommended dosage instructions.
While receiving "Nitrosorbid" may be pain in the head, dizziness, drowsiness, blurred vision, tachycardia, nausea, vomiting, dryness of the oral mucosa, in rare cases, possible heartburn.
Store in a cool, dry, out of reach of children.The shelf life of the drug is 2 years.