penicillin



Start of development of penicillin was initiated in 1928.That's when the Scottish bacteriologist Alexander Fleming discovered the unique action of a substance that releases mold fungus.In 30-ies of XX century it has already begun active clinical trials of new drugs, and in ten years, unfolded its mass production.

penicillin antibiotics are truly unique in their properties.They have a broad range of effective dosages, sufficiently low in comparison with many other drugs, toxic effects on the body.They are rapidly absorbed and have an almost immediate effect.And also rapidly cleared from the human body.

All penicillin antibiotics can be divided into four groups.The first is a naturally occurring penicillins ("Penicillin" and "Phenoxymethylpenicillin").The
se drugs have a narrow spectrum of activity as influenced by enzymes produced by microorganisms (penicillinases).During the second and third groups include karboksipenitsilliny ("ticarcillin" and "Karbpenitsillin").These drugs are less susceptible to penicillinases therefore have the best results in the fight against infection.The fourth group of medicines include broad-spectrum penicillins ("mezlocillin" "azlocillin" "Metsillam" et al.).It is best to fight infectious diseases.

Features of the antibiotic and its effects on the body



Doctors prescribe penicillin to treat infections of the gastrointestinal tract, diseases of the upper and lower respiratory tract infections, urinary infections.Also it is used in sexually transmitted diseases and ophthalmic procedures.

But despite the fact that the antibiotics of the penicillin group is quite well tolerated by the human body, yet they can cause some side effects.In particular, allergic reactions (dermatitis, rashes, swelling of the mucous membranes, arthritis, bronchospasm, etc.), Toxic effects (diarrhea, nausea, stomatitis, goiter, candidiasis, etc.), Neurotoxic reactions (convulsions, hallucinations, impaired blood pressure).

best therapeutic effect is achieved if penicillin administered intramuscularly.However, when there is no opportunity to put injections, oral medication and therapy gives positive results.For such purposes the best fit "amoxicillin" and "Phenoxymethylpenicillin".