indication for the drug "Thrombotic ASS" are: primary and secondary prevention of stroke, acute myocardial infarction, deep vein thrombosis of extremities, pulmonary embolism, the treatment of unstable angina.The mechanism of action of aspirin is that it blocks the action of the enzyme cyclooxygenase 1, and gives the synthesis of substances capable of causing an inflammatory response (prostaglandins, prostacyclin, etc.).Particularly active antiplatelet effect is in respect of platelet adhesion preventing them together.
¬ęThrombotic ASS" inhibits the formation of thromboxane A2, reduces blood levels of certain clotting factors, increases fibrinolytic activity of plasma.Aspirin is actively absorbed from the digestive tract and in the blood, it is bound to plasma proteins.As a result of metabolism in liver enzymes occurs
substantial portion of the drug in the process produces the active metabolite - salicylic acid.
The drug should be taken before meals, preferably not on an empty stomach in order to reduce possible side effects.It is recommended to drink plenty of water medicine.For the prevention of "Thrombotic ACC" take a long time, duration of treatment and the daily dose should be determined by the attending physician.In order to prevent myocardial infarction, stroke, to treat angina drug administered in a daily amount of 50-100 mg.For the prevention of deep vein thromboembolism and pulmonary arteries appoint 100-200 mg per day.
not recommended "Troma ACC" in conjunction with other NSAIDs.Tool counter with possible bleeding from the gastrointestinal tract (exacerbation of gastric ulcers and 12 duodenal ulcer), hemorrhagic diathesis, intolerance of aspirin and other NSAIDs, severe hepatic, renal, chronic heart failure, bronchial asthma induced by aspirin, while taking "Methotrexate".
not use "Thrombotic ACC" in the 1st and 3rd trimesters of pregnancy, lactation, in children and adolescents up to 18 years.With careful preparation is used in peptic ulcer disease in remission, gout, chronic diseases of the respiratory system, prior to surgery."Thrombotic ASS" may cause the following side effects: nausea, vomiting, abdominal pain, dizziness, gastrointestinal and other bleeding, changes in clinical and biochemical blood tests.