How to apply "Naloxone┬╗

Sobering drugs are used to derive from the state of acute alcohol intoxication.Opioid receptor antagonist is "Naloxone", it eliminates the central and peripheral opioid effects, including hypotension and respiratory depression.The drug is used in acute alcohol poisoning (including the coma), with an overdose of opioids, barbiturates, benzodiazepines, as a diagnostic tool in patients with suspected drug dependence.

┬źNaloxone" administered intravenously, intramuscularly or subcutaneously in a dose of 400 micrograms.If the effect is not sufficiently pronounced, the injection was repeated at the same dose after two or three minutes."Naloxone" is contraindicated in case of hypersensitivity to its components.Side effects of th
e drug: tachycardia, nausea, vomiting, itching, rash, sweating, tremor (with the rapid introduction), after administration of high doses may develop hypertension or hypotension, ventricular fibrillation, ventricular tachycardia, pulmonary edema.

Other sobering drugs

By psychostimulants, relieves alcohol withdrawal syndrome include benzodiazepine tranquilizers ("hlozepida", "Sibazon", "Phenazepam").They are taken to the usual dose (0.5-1 mg) every four to six hours to achieve a normal state or before the onset of sleep.These drugs are contraindicated in acute poisoning with alcohol, myasthenia gravis, angle-closure glaucoma, chronic obstructive pulmonary disease in its advanced stage, acute respiratory failure, severe depression at the age of 18 years.

At a headache caused by hangover state, use "Alka-Seltzer" (NSAIDs), it includes acetylsalicylic acid, sodium carbonate, citric acid.A tablet formulation is to be dissolved in a glass of water and taken orally (up to 6 times a day).The interval between doses should be at least 4 hours."Alka-Seltzer" is contraindicated in case of hypersensitivity to the drug, erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase), hemorrhagic diathesis, concomitant use of "Metotreksa", "aspirin" asthma.If you can take the hangover "Aspirin" in a single dose, which is 0.5-1 grams.Intervals between doses should be at least 4 hours.The maximum daily amount should not exceed three grams (six tablets).Contra the "aspirin" the same as that of the "Alka-Seltzer."