What can replace "Vilprafen»



«Vilprafen" has different dosage forms.Sales can find tablets containing 500 mg of josamycin, the suspension (10 ml containing 300 mg of josamycin) and water-soluble tablets (one piece contains 1 g of active substance).A suitable form of the drug can recommend a doctor or pharmacist pharmacy.The question of whether we can replace "Vilprafen" another drug of the same pharmacological group, to decide physician.Macrolide antibiotics are "erythromycin", "clarithromycin" ("Binoklar" "Klabaks" "Klareksid" "Klaritsin" "Klatsid" "Fromilid"), "azithromycin" ("azivok" "Sumamed", "Azilid "" Zitrolid "" Sumazid "" Hemomitsin) "Roxithromycin" ("Brilid" "Rowan," "hydroxide"
"Roksimizan" "Roxithromycin"), "Elroks" "Spiramycin" ("Rovamycinum")," midecamycin "" Macropen ".

mechanism of action of these drugs is based on inhibition of protein synthesis in the cells of pathogens.As a rule, macrolides inhibit the vital activity of bacteria (bacteriostatic effect), in large doses, they can act bactericidal (kills bacteria).These antibiotics show active action against staphylococci, streptococci, pneumococci, hladimy, mycoplasma, ureaplasma, Legionella, pertussis, diphtheria.These preparations also possess immunomodulating and antiinflammatory properties.The first macrolide considered "Erythromycin" currently most pathogens has developed resistance to it.The highest activity against Haemophilus stick shows "Azithromycin" against ureaplasma, mycoplasma, chlamydia most active "Laritromitsin" and "Vilprafen.""Midecamycin" effective against many infectious agents, including intracellular.

Possible side effects of antibiotics, macrolides



macrolides Side effects depend on the drug and on its dose.Patients may appear disruption of the gastrointestinal tract (nausea, vomiting, abdominal pain).When you receive a "Erythromycin" these phenomena are caused by the fact that the substance binds to receptors motilin and enhances motor skills."Azithromycin" and "clarithromycin" better tolerated, but may cause gastrointestinal disturbances.

Less evident ototoksicheskoe and hepatotoxic effects of antibiotics, macrolides.Hepatotoxic effects in the form of cholestatic jaundice often manifests "Erythromycin".Ototoxic effect (reversible hearing impairment) when taking these drugs into a relatively rare, but with the introduction of "Erythromycin" intravenous hearing impairment were identified in 20% of patients.In rare cases, admission macrolides appear allergic skin reactions.