purpose of treating acute or chronic pyelonephritis is the elimination of the inflammatory process.When prescribing antibiotics, it is important to determine the type of the pathogen of the disease, so taking these drugs alone is unacceptable.For the treatment of pyelonephritis may appoint penicillins ("Ampicillin" "Amoxicillin", etc.), which are effective in relation to the enterococci, Proteus, E. coli.However, this group of antibiotics has a serious drawback - the drugs can lose their medicinal properties by the action of enzymes produced by certain bacteria.Such drugs are generally administered for the treatment of pyelonephritis during pregnancy.The exception is a modified form of the antibiotic amoxicillin - "Flemoklav Soljutab."In its
composition contains clavulanic acid, which reduces the adaptability of the bacteria to the drug.
most common in pyelonephritis prescribe antibiotics cephalosporin group, which are divided into four generations.The first are "cephradine", "cefazolin", "Cephalexin".They take an active effect against gram-positive bacteria, including penicillin-resistant.These drugs are not indicated in the acute form of the disease.By the second-generation drugs is "Tseforuksim", which is used only in the treatment of chronic processes.By the third generation drugs include: "cefixime" "Ceftriaxone", "ceftibuten."They are effective in the treatment of complicated forms of pyelonephritis, have an active effect against Pseudomonas aeruginosa.The fourth generation of this group of antibiotics, which include "Cefepime," has all the positive qualities of predecessors, as well as targeting against gram-positive and gram-negative pathogens forms.
One of the most modern drugs are antibiotics, fluoroquinolones, "Ciprofloxacin", "pefloksatsina", "Ofloxacin".These drugs are effective against almost all pathogens pyelonephritis and have minimal nephrotoxicity.For drugs, a second-generation fluoroquinolones are "Moxifloxacin", "lomefloxacin", "sparfloxacin," "Ciprofloxacin", "norfloxacin".Antibiotics-fluoroquinolones are contraindicated during pregnancy and lactation and children under 16 years.Aminoglycoside antibiotics-("Gentamycin", "Tobramycin" "Amikacin") to be applied under strict medical supervision as they have a powerful antibacterial action and has high nephrotoxicity.These drugs are contraindicated in the elderly.