With a lack or an excess in the body of potassium and magnesium in humans can cause serious disorders of the cardiovascular system, brain and kidneys.Also, frequent arrhythmias, fatigue, swelling of the lower legs, the face.With all of these ailments can deal a drug as Pananginum, which is a real vitamin for the heart.

General description of the preparation



Panangin (or asparkam) is a combined preparation.It is available in tablets, in the form of a disk, usually white, or almost white, film-coated glossy or slightly roughened surface.Virtually odorless.Also available in a solution for injection

Each tablet contains 140 mg of magnesium asparaginate, 158 mg of potassium asparaginate.Aids are colloidal anhydrous silica, magnesium stearate, talc, corn starch, povidone, potato starch, titanium dioxide, Eudragit E 100%
, macrogol 6000.


Pharmacological action



Panangin helps to normalize the levels of potassium and magnesium in the cellstissues.Magnesium and potassium ions affect the contractile effects of the cardiac muscle, thereby reducing the risk of oxygen starvation (anoxia).As a result, it prevents the development of cardiac arrhythmias, and also improves the function of the gastrointestinal tract and contraction of skeletal muscles.

Indications



The drug Pananginum designated as adjunctive therapy in heart failure, cardiac arrhythmias induced hypokalemia, which is possible with intoxication cardiac glycosides such as digoxin, digitoxin, gitoksin, lantazid, kordigit and lrugimi andwhen receiving prednisolone, hydrocortisone and certain diuretics.It is recommended to use panangina after infarct states, disorders of heart rhythm, usually caused by ventricular arrhythmias.Pananginum useful in the treatment and prevention of coronary heart disease, myocardial infarction, cardiac arrhythmias, in treatment of glycosides, while the application of urinary means, metabolic disorders.Prescribers and after serious infectious diseases involving heavy losses of the liquid.Useful Pananginum blood transfusion, severe malnutrition, depleted magnesium ions and potassium. panangina solution for injection can be administered only by intravenous, intramuscular use of injections can cause tissue irritation.


Assign the drug and children.For example, in infancy it is recommended to strengthen the heart muscle newborns with open heart defects, removal of seizures. Newborns sometimes after strong crying or elevated temperature may occur cramps.These symptoms are usually observed at the deficit in the body potassium and magnesium ions.
And then in this case there is a need to appoint panangina that is well tolerated in children.

Pananginum Quite often prescribed to pregnant women.With his help during pregnancy can fight puffiness, toxicosis.The positive impact Pananginum has on the heart muscle and kidney woman.It also promotes the proper development of the fetus, especially the formation of its brain and muscle apparatus.

Dosing and Administration



Panangin administered orally or intravenously.If it is a tablet, then they are administered to adults 1-2 pieces 2-3 times a day for 14 days.If necessary, the dose prescribed by the doctor can be expanded to three tablets at once to three times a day.Then gradually reduce the dose.

When arrhythmia solution panangina administered only intravenously, drip 1-2 ampoules, one-time fee.If necessary, the procedure can be repeated after 4-6 hours.

Side effects



With proper use and compliance with dosage side effects panangina not revealed.In rare cases, patients with gastric inflammation, low acidity, cholecystitis may experience a burning sensation, stomach discomfort.Also receiving panangina may have low blood pressure, nausea, vomiting, diarrhea, skin redness, a burning sensation.At high doses the possibility of increasing the number of bowel movements.

Contraindications



Application panangina contraindicated in case of hypersensitivity to one or more components of the drug, acute or chronic kidney failure, Addison's disease, cardiogenic shock.It is not recommended to combine the drug with alcohol and drugs.And in some cases, against the background of the use panangina pronounced intoxication can be dangerous.

Effect on ability to drive vehicles



The study of the drug were found negative impact on the ability to drive vehicles or operate complex, requiring special attention mechanisms.

Drug Interactions

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Panangin may cause the process to reduce vsasyvaniyai tetracycline, sodium fluoride, iron salts, therefore reception panangina should be administered 3 hours after receiving the above-mentioned drugs.With simultaneous use panangina increased risk with potassium-sparing diuretics may cause arrhythmia and asystole.

Terms and method of storage.Leave a pharmacy



Panangin should be stored in a dry, dark place at a temperature of 15 to 30 degrees.
tablets Shelf life - 3 years, vials with a solution for injection - 2 years.

sold without prescription.