How does "Analgin»



«Analgin" capable of blocking cyclooxygenase - an enzyme involved in the synthesis of prostaglandins (a group of substances involved in the formation of pain and inflammation).As a result of the synthesis of prostaglandins, arachidonic acid, bradykinin slows pain impulses are blocked, heat transfer is enhanced, the body temperature decreases.

«Analgin" is available in tablets, capsules (solution for intramuscular and intravenous administration), rectal suppositories.Tablets, suppositories The drug takes effect 15-30 minutes after application.The maximum concentration of agents in the blood within an hour and a half after the application.Prick the drug will work in 10-20 minutes.Duration of action "Analgin" - 4-8 hours.The ingestion of the drug active ingredient 80-90% digested within the gastrointestinal tract, a small portion binds to pl
asma protein, the major concentration is in the body in the unbound form. Metamizol sodium by itself has no pharmacological effect, a therapeutic effect is developing after conversion by the liver into a metabolite.

How to apply "Analgin»



«Analgin" is used for rheumatism, fever, acute respiratory diseases, pain of various origins (neuralgia, neuritis, myositis, radiculitis).The drug is usually prescribed to 250-500 mg two to three times a day.The maximum allowable single dose - not more than 1 g daily - no more than 3 years

intramuscularly or intravenously agent is used in severe pain 250-500 ml three times per day.Children under the age of one year of drug administered in the form of intramuscular injections two to three times a day, the rate of five to ten milligrams per kilogram of body weight.Adults "Analgin" in rectal suppositories used in dosages 300 mg 650.1000.Rectal suppositories for children administered, given the disease and age.For children from six months to a year is recommended suppositories 100 mg, children between 1-3 years prescribed suppositories 200 mg, for children 3-7 years, light candles 200-400 mg for children aged 8-14 years - 200-600 mg. After rectal administration of the drug need to lie down for a while.

«Analgin" may have the following side effects: skin rash, leukopenia, skin rash, fever, headache, dizziness.The drug is contraindicated in diseases of the blood, oppression of blood, during pregnancy and breastfeeding, dysmenorrhea, liver, kidney failure, aspirin asthma, anemia.