«have" indicated for the treatment of inflammatory diseases associated with pain symptoms: degenerative inflammatory diseases of the musculoskeletal system (osteoarthritis, ankylosing spondylitis, rheumatoid arthritis, psoariatichesky arthritis, tendonitis, bursitis,worsening of gout).Effectively relieves pain after injuries of muscles, joints, when algodismenoree, reduces the temperature of inflammations of infectious nature."Have" include in the complex therapy of infectious diseases of upper respiratory tract, accompanied by fever, pain.
2 tablets of the drug must be taken orally, during or after meals with water.When mild to moderate pain in adults and children from 12 years appoint 200-400 mg 2-3 times a day.At high temperatures, adults and children from 12 years old to take 200-400 mg once.If
the temperature does not decrease after 4 hours was repeated reception.The maximum permitted daily amount "to have" for adults, children from 15 - 1200 mg, for children from 12 years - 1,000 mg.The interval between doses should be not less than 4 hours.For elderly adjust the dosage is required.
«to have a" can have the following side effects: constipation, abdominal pain, diarrhea, heartburn, nausea, vomiting, flatulence, ulcerative lesions of the gastrointestinal tract, headache, edema.In some cases, after ingestion damaged liver tissue, decreased urine output, increasing amounts of uric acid in serum, developing impaired hematopoiesis.Sometimes there are skin rash, itching, appears aseptic meningitis, asthma, shortness of breath, tachycardia, decreased blood pressure.
«have" is contraindicated in case of hypersensitivity to the components of acetylsalicylic acid, for children up to 12 years.Do not prescribe the means in the 3rd trimester of pregnancy, asthma, severe pathology of the liver, kidneys, blood vessels, heart, ulcerative lesions of the gastrointestinal tract, gastrointestinal bleeding.In an application with ingibitoroami ACE and beta-blockers "have" reduced their antihypertensive effect.
drug reduces the effect of "hydrochlorothiazide", "Furosemide" and other diuretics.Since ibuprofen enhances the effects of anticoagulants, while receiving more likely to develop gastrointestinal bleeding."Aspirin" reduces the concentration of ibuprofen in the blood plasma.In cases of "have" with corticosteroids increases the risk of side effects from the digestive tract.