time penicillin was it?



Medicine since the days of penicillin has gone far ahead, creating a new generation of powerful drug analogues.The reason that modern doctors have to apply powerful antimicrobial agents is that harmful bacteria have time to adapt to penicillin.Microbes have adapted and began to produce a special enzyme - penicillinase, which is capable of destroying antibiotics.


Antibiotics new generation



Most newer antibiotics work selectively, t. E. The action of microorganisms is directed against one or two species.Today in curative medicine widely used antibiotics from the group of fluoroquinolones, cephalosporins, imipenem, macrolides, penicillins.The most powerful antibiotics are br
oad-spectrum antibiotics that kill gram-positive and Gram and bacteria.


Cephalosporins



belong to this group the most powerful antibiotics with a broad spectrum of activity, working bactericidal.These drugs are well tolerated, having minimal side effects.Now the group has four generations of cephalosporins.
• First-generation.
Excellent work against staph infections cefadroxil ("Biodroksil", "Durotsef"), cefazolin ("Kefzol", "Rizolin"), cephalexin ("Ospeksin", "Sporideks").

• second-generation drugs.
Medications prescribed to combat intestinal and Haemophilus influenzae, Klebsiella.This cefuroxime ("Zinnat" "Ketotsef" "Aksetin" "Ketotsef"), cefaclor ("Taratsef" "Vertsef").

• Preparations of the third generation.
well established in the treatment of diseases such as pyelonephritis, meningitis, pneumonia, infections of the abdomen, osteomyelitis.These include ceftazidime ("Fotrazim" "Fortum"), ceftriaxone ("Tortsef" "Lendatsin"), ceftazidime ("Tsefobid" "Medotsef"), cefotaxime ("Tsefosin" "Claforan").

• Preparations fourth generation - the strongest of cephalosporins ("Cefepime").
range of application is much wider than the previous group, together with the more and the list of side effects: goiter, nephrotoxicity, neurotoxicity haematotoxicity.


Macrolides



Antibiotics narrow application are macrolides that have proven themselves in the struggle against Gram-positive microorganisms.Action macrolides Stops directed to bacterial cell growth, while they do not inhibit the immune system.

Products in this group include "erythromycin", "Spiramycin" "oleandomycin" "Clarithromycin", "azithromycin", "Josamycin" "Roxithromycin".The most powerful of macrolides are considered "Josamycin" and "clarithromycin".These medications are prescribed for the treatment of stomach ulcers, sinusitis, ear infections, respiratory infections, and Chlamydia.