What is "Fraksiparin»
main active substance "Fraksiparina" is nadroparin calcium, which is a low molecular weight heparin obtained by depolymerization of conventional heparin.By comparison, "Fraksiparin" has higher antithrombotic activity and acts directly on the primary hemostasis.
«Fraksiparin" is available in different dosages.Typically, they are measured in terms of antithrombotic activity factor and mean anti-Xa IU.The drug release in dosages 2850, 3800, 5700, 7600, 9500. As an adjuvant, which was diluted nadroparin calcium, taking dissolved calcium hydroxide solution or dilute hydrochloric acid.
This drug is used for the prevention of thrombus formation, as well as for the treatment of thromboembolism.It is one of the drugs of choice in the prevention of myocardial infarction.
Dosage and Administration
First of all, it should be noted that th
order to designate the desired dose to the patient, it is necessary to know the exact weight.Doses "Fraksiparina" differ by a few tenths of a milliliter, but their excess can lead to bleeding.Thus, humans weighing 51 kg, to be administered 0.2 ml, individuals with a weight of 51 to 70 kg - 0.3 ml, and more than 70 kg - 0.4 ml.
Typically, the drug is administered two hours prior to surgery, but if the operation has a rather high thrombotic risk, it is administered within 12 hours at a dose 38 IU anti-Xa.After the operation "Fraksiparin" is administered at 12 hours after the operation in the amount of 57 anti-Xa IU.The next three days, repeat the course.
the treatment of unstable angina or myocardial infarction, nadroparin calcium is administered twice a day with an interval of 12 hours.Dosage is 86 while the anti-Xa IU.The initial dose is 0.4 ml, and then gradually increased.
However, it should be remembered that it is impossible to completely eliminate the thrombotic activity.Therefore, use of the drug is recommended only in a hospital.It is also important to pay special attention to contraindications and side effects.