Guide
1
¬ęTorizel" administered intravenously (drip) 25 mg once a week.IV should be done in 30-60 minutes.About half an hour before the procedure, patients need to enter "Diphenhydramine" (intravenously, in an amount of 25-50 mg) or some other antihistamines.Changing the number of "Torizela" depending on the age or sex of charge.In renal and liver failure (with mild or moderate-severe), dosage adjustment is not necessary.In patients with severe liver disease, the dose "Torizela" should not be more than 10 mg once a week.
2
Treatment "Torizelom" continue to confirm its clinical efficacy, or until it is time, until it was revealed unacceptable toxicity.When possible adverse reactions may require temporary cessation of administration of the drug or reducing its dose.If the break in treatment does not lead to the elimination of unwanted re
actions dose "Torizela" is reduced by 5 mg per week.
3
Preparation of solutions' Torizela "carried out in an area protected from excessive light and from direct sunlight.
To prepare a stock solution contents of the vial with the solvent must be added to the vial with the concentrate, carefully flip it, not shaken.Should get a uniform mixture without air bubbles, clear or slightly cloudy.The resulting solution was used for solution for infusion, it must be used within 24 hours.2.5 ml "Torizela" was added to 250 ml of 0.9% sodium chloride solution, the resulting infusion solution is stirred by avoiding excessive shaking.It should be used within six hours (including time dropper - 30-60 minutes).
4
the treatment "Torizelom" observed the following side effects: hypersensitivity reactions, glucose intolerance, interstitial lung disease, intracranial hemorrhage, intestinal perforation, renal failure, complicated wound healing.The most common adverse reactions are: nausea, abdominal pain, rash, anemia, anorexia, fatigue, cataracts, disorders lacrimation, conjunctivitis, neytroperiya, leukopenia, lymphopenia, venous thromboembolism, thrombophlebitis, hypertension.Also may develop shortness of breath, coughing, nosebleeds, pain in the back, in the joints, chest pain, swelling of the face, fever.